BDBM395077 US10308615, Example 88::{6-[(4- methoxybenzyl) amino]pyridazin-3- yl}[3- (trifluoromethyl) phenyl]methanone

SMILES COc1ccc(CNc2ccc(nn2)C(=O)c2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=XCAPUVSPAQRLOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395077   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395077(US10308615, Example 88 | {6-[(4- methoxybenzyl) am...)
Affinity DataIC50: 1.86E+4nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM395077(US10308615, Example 88 | {6-[(4- methoxybenzyl) am...)
Affinity DataIC50: 9.30nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent