BDBM394669 (3-chlorophenyl){2- [(2-phenylpropan-2- yl)amino]pyrimidin- 5-yl}methanone::US10308615, Example 25

SMILES CC(C)(Nc1ncc(cn1)C(=O)c1cccc(Cl)c1)c1ccccc1

InChI Key InChIKey=CNHIYUMHLCGGJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 394669   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394669(US10308615, Example 25 | (3-chlorophenyl){2- [(2-p...)
Affinity DataIC50: 74.1nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394669(US10308615, Example 25 | (3-chlorophenyl){2- [(2-p...)
Affinity DataIC50: 64.5nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394669(US10308615, Example 25 | (3-chlorophenyl){2- [(2-p...)
Affinity DataIC50: 11.5nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent