BDBM394662 (3-methoxyphenyl)(2-{[1-(pyrimidin-5-yl)cyclopropyl]amino}pyrimidin-5-yl)methanone::US10308615, Example 18

SMILES COc1cccc(c1)C(=O)c1cnc(NC2(CC2)c2cncnc2)nc1

InChI Key InChIKey=XISOVJXHGTWKNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394662   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394662(US10308615, Example 18 | (3-methoxyphenyl)(2-{[1-(...)
Affinity DataIC50: 26.5nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394662(US10308615, Example 18 | (3-methoxyphenyl)(2-{[1-(...)
Affinity DataIC50: 12.3nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent