BDBM394652 (−)-4-(1-{[5-(3-cyanobenzoyl)pyrimidin-2-yl]amino}ethyl)benzamide::US10308615, Example 9

SMILES C[C@@H](Nc1ncc(cn1)C(=O)c1cccc(c1)C#N)c1ccc(cc1)C(N)=O

InChI Key InChIKey=PZMCWUVNRFWFRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394652   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394652(US10308615, Example 9 | (−)-4-(1-{[5-(3-cyan...)
Affinity DataIC50: 10.3nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394652(US10308615, Example 9 | (−)-4-(1-{[5-(3-cyan...)
Affinity DataIC50: 41.3nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent