BDBM394646 3-({2-[(2-phenylpropan-2-yl)amino]pyrimidin-5-yl}carbonyl)benzonitrile::US10308615, Example 3

SMILES CC(C)(Nc1ncc(cn1)C(=O)c1cccc(c1)C#N)c1ccccc1

InChI Key InChIKey=VCAAYIIGVCSPBP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 394646   

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394646(US10308615, Example 3 | 3-({2-[(2-phenylpropan-2-y...)
Affinity DataIC50: 13.6nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394646(US10308615, Example 3 | 3-({2-[(2-phenylpropan-2-y...)
Affinity DataIC50: 15.3nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM394646(US10308615, Example 3 | 3-({2-[(2-phenylpropan-2-y...)
Affinity DataIC50: 75nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent