BDBM394592 (2R)-2-[4-[3-amino- 6-(2- hydroxyphenyl) pyridazin-4-yl]pyrazol- 1-yl]-N,N-dimethyl- propanamide::US10308614, Example 195

SMILES C[C@H](C(=O)N(C)C)n1cc(cn1)-c1cc(nnc1N)-c1ccccc1O

InChI Key InChIKey=UBFNRPGSFRMZGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394592   

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandPNGBDBM394592(US10308614, Example 195 | (2R)-2-[4-[3-amino- 6-(2...)
Affinity DataIC50: 21.7nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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