BDBM394542 (4-(3-amino-6-(2-::US10308614, Example 143

SMILES Nc1nnc(cc1N1CCN(C(CO)C1)C(=O)c1cncs1)-c1ccccc1O

InChI Key InChIKey=JHRGZYTZACMRJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394542   

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandPNGBDBM394542(US10308614, Example 143 | (4-(3-amino-6-(2-)
Affinity DataIC50: 20.6nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent