BDBM394520 3-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)-N,N-dimethyl-3,8-diazabicyclo[3.2.1]octane-8-carboxamide::US10308614, Example 121

SMILES CN(C)C(=O)N1C2CCC1CN(C2)c1cc(nnc1N)-c1ccccc1O

InChI Key InChIKey=HBZXGZNCRIGZJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394520   

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandPNGBDBM394520(US10308614, Example 121 | 3-(3-amino-6-(2-hydroxyp...)
Affinity DataIC50: 22.5nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent