BDBM394481 Enantiomer 1 and Enantiomer 2 of 2-(6-amino-5-(4-(1-phenylethyl)piperazin-1-yl)pyridazin-3-yl)phenol::US10308614, Example 81

SMILES C[C@@H](N1CCN(CC1)c1cc(nnc1N)-c1ccccc1O)c1ccccc1

InChI Key InChIKey=MBDFNLARUDVNEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394481   

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandPNGBDBM394481(US10308614, Example 81 | Enantiomer 1 and Enantiom...)
Affinity DataIC50: 19.1nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
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