BDBM394313 US10428087, Example 33::US10829502, Example 33::US11401280, Example 33::US9975907, Example 33

SMILES CC(Nc1nc(N)nc2[nH]cnc12)c1nc2scc(C)n2c(=O)c1-c1ccccc1F

InChI Key InChIKey=XMNKUSOVDDDLLY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 394313   

LigandPNGBDBM394313(US9975907, Example 33 | US10428087, Example 33 | U...)
Affinity DataIC50: 50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

LigandPNGBDBM394313(US9975907, Example 33 | US10428087, Example 33 | U...)
Affinity DataIC50: 50nMAssay Description:Assay A2: The kinase reaction was conducted in clear-bottom 96-well plate from Thermo Fisher Scientific in a final volume of 24 μL. Inhibitors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

LigandPNGBDBM394313(US9975907, Example 33 | US10428087, Example 33 | U...)
Affinity DataIC50: 50nMAssay Description:Example A3: The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent

LigandPNGBDBM394313(US9975907, Example 33 | US10428087, Example 33 | U...)
Affinity DataIC50: 50nMAssay Description:PI3Kα, PI3Kβ, PI3Kγ: The kinase reaction was conducted in clear-bottom 96-well plate from Thermo Fisher Scientific in a final volume o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
Go to US Patent