BDBM394147 5-[5-chloro-2- (1H-tetrazol- 1-yl)phenyl]- 2-[2-phenyl-1- (3-piperidin-4- ylphenyl)ethyl] pyridine 1- oxide::US9975874, Example 20

SMILES [O-][n+]1cc(ccc1C(Cc1ccccc1)c1cccc(c1)C1CCNCC1)-c1cc(Cl)ccc1-n1cnnn1

InChI Key InChIKey=RSTQQFVWLLPAOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394147   

TargetCoagulation factor XI(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394147(US9975874, Example 20 | 5-[5-chloro-2- (1H-tetrazo...)
Affinity DataIC50: 216nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
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