BDBM394085 US9974785, Example 4

SMILES FC(F)c1cn(c2cccc(N3CCNCC3)c12)S(=O)(=O)c1ccccc1Br

InChI Key InChIKey=UHHZUOXKOCAANR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394085   

Target5-hydroxytryptamine receptor 6(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM394085(US9974785, Example 4)
Affinity DataKi:  1.10nMAssay Description:32 μg membrane proteins of CHO cell expressing human 5-HT6 receptor, 2 nM of radioactive marker [3H]LSD, a compound of the present invention hav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM394085(US9974785, Example 4)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in CHO cells assessed as inhibition constant incubated for 120 mins by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed