BDBM393993 5-{7-fluoro-4-[(trans-4- morpholin-4- ylcyclohexyl)amino] quinazolin-6-yl}pyridin-3- ol::US9969749, Example 1-84

SMILES Oc1cncc(c1)-c1cc2c(N[C@H]3CC[C@@H](CC3)N3CCOCC3)ncnc2cc1F

InChI Key InChIKey=SBLBOUGCCWYNOD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393993   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM393993(US9969749, Example 1-84 | 5-{7-fluoro-4-[(trans-4-...)
Affinity DataIC50: 1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
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Date in BDB:
4/6/2020
Entry Details
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