BDBM393975 3-fluoro-5-{4-[(trans- 4-morpholin-4- ylcyclohexyl)amino] quinazolin-6-yl}phenol::US9969749, Example 1-66

SMILES Oc1cc(F)cc(c1)-c1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c2c1

InChI Key InChIKey=VZMGRASFXPEYDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393975   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM393975(US9969749, Example 1-66 | 3-fluoro-5-{4-[(trans- 4...)
Affinity DataIC50: 5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
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