BDBM393724 US9969724, Example 53

SMILES Nc1noc2c(ccc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-c1ccnc(CO)c1

InChI Key InChIKey=HKAAIBGKNYKYMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393724   

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM393724(US9969724, Example 53)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent