BDBM393585 US9969687, Compound 261

SMILES COc1ncc(C)cc1N1C(=O)c2c(C1=O)c(NS(=O)(=O)c1ccc(cc1)C(C)(C)C)ccc2Cl

InChI Key InChIKey=PZMQLIASRUDGIO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 393585   

TargetC-C chemokine receptor type 9(Human)
Norgine

US Patent
LigandPNGBDBM393585(US9969687, Compound 261)
Affinity DataKi:  11nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 9(Human)
Norgine

US Patent
LigandPNGBDBM393585(US9969687, Compound 261)
Affinity DataKi:  16nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed