BDBM393399 3-((3'-Methoxy-[1,1'-biphenyl]-4-yl)(phenyl)methoxy)azetidine-1-carbonitrile::US9963444, Example 100

SMILES COc1cccc(c1)-c1ccc(cc1)C(OC1CN(C1)C#N)c1ccccc1

InChI Key InChIKey=SGFMJKFESZEQMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 393399   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393399(US9963444, Example 100 | 3-((3'-Methoxy-[1,1'-biph...)
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393399(US9963444, Example 100 | 3-((3'-Methoxy-[1,1'-biph...)
Affinity DataIC50: 12nMAssay Description:Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed