BDBM393386 US9963444, Example 87

SMILES N#CN1CC(C1)OCc1ccc(Oc2ccccc2)cc1-c1ccccc1

InChI Key InChIKey=BIFMPKUNYXQFNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 393386   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393386(US9963444, Example 87)
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393386(US9963444, Example 87)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed