BDBM393376 3-((4'-Fluoro-[1,1'-biphenyl]-4-yl)methoxy)azetidine-1-carbonitrile::US9963444, Example 77

SMILES Fc1ccc(cc1)-c1ccc(COC2CN(C2)C#N)cc1

InChI Key InChIKey=BKJDTTMYPPBQSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 393376   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393376(US9963444, Example 77 | 3-((4'-Fluoro-[1,1'-biphen...)
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393376(US9963444, Example 77 | 3-((4'-Fluoro-[1,1'-biphen...)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed