BDBM393363 3-([1,1'-Biphenyl]-4-ylmethoxy)azetidine-1-carbonitrile::US9963444, Example 64

SMILES N#CN1CC(C1)OCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ZSTZNGPOKKKVCT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 393363   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393363(US9963444, Example 64 | 3-([1,1'-Biphenyl]-4-ylmet...)
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393363(US9963444, Example 64 | 3-([1,1'-Biphenyl]-4-ylmet...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM393363(US9963444, Example 64 | 3-([1,1'-Biphenyl]-4-ylmet...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of NAAA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed