BDBM393288 US9963443, Reference Example 14

SMILES CN([C@@H]1CCOC1)C(=O)C1CCN(CC1)c1cnccc1-n1cc(Cl)cn1

InChI Key InChIKey=UILLLRHSHNNGLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393288   

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393288(US9963443, Reference Example 14)
Affinity DataIC50: 17nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent