BDBM3928 5-Substituted 1-Phenylbenzimidazole 17::5-[3-(N,N-Dimethylamino)propoxy]-1-phenylbenzimidazole Dihydrochloride::dimethyl({3-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]propyl})amine

SMILES CN(C)CCCOc1ccc2n(cnc2c1)-c1ccccc1

InChI Key InChIKey=TVCMMAFYYAKVLR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3928   

TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM3928(5-[3-(N,N-Dimethylamino)propoxy]-1-phenylbenzimida...)
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM3928(5-[3-(N,N-Dimethylamino)propoxy]-1-phenylbenzimida...)
Affinity DataIC50: 4.10E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM3928(5-[3-(N,N-Dimethylamino)propoxy]-1-phenylbenzimida...)
Affinity DataIC50: 1.40E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2005
Entry Details Article
PubMed