BDBM392689 US10301286, Example 92

SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C1CCOCC1)[C@@H](Cc1ccc(cc1F)C1CC1)C(O)=O

InChI Key InChIKey=KNNYTMIFFZWBJB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 392689   

TargetMelanocortin receptor 4(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392689(US10301286, Example 92)
Affinity DataEC50:  12nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
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TargetMelanocyte-stimulating hormone receptor(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392689(US10301286, Example 92)
Affinity DataEC50:  1.70E+3nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetMelanocortin receptor 3(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392689(US10301286, Example 92)
Affinity DataEC50:  1.80E+3nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent