BDBM392686 US10301286, Example 78

SMILES C[C@H]([C@H](N1CCN([C@@H](C)C1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C1CCOCC1)C(O)=O)c1ccc(C)cc1

InChI Key InChIKey=RWRSCOMGJJZSHB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 392686   

TargetMelanocortin receptor 4(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392686(US10301286, Example 78)
Affinity DataEC50:  16nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetMelanocyte-stimulating hormone receptor(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392686(US10301286, Example 78)
Affinity DataEC50:  1.00E+3nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetMelanocortin receptor 3(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392686(US10301286, Example 78)
Affinity DataEC50:  680nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent