BDBM392681 US10301286, Example 57

SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](CC1CCCCC1)C(O)=O

InChI Key InChIKey=NOKKTMJQBGAGQB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 392681   

TargetMelanocortin receptor 4(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392681(US10301286, Example 57)
Affinity DataEC50:  120nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
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TargetMelanocyte-stimulating hormone receptor(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392681(US10301286, Example 57)
Affinity DataEC50:  1.90E+3nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetMelanocortin receptor 3(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392681(US10301286, Example 57)
Affinity DataEC50:  2.40E+3nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent