BDBM392662 US10301286, Example 88

SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C1CCOCC1)[C@@H](Cc1c(C)cc(C)cc1F)C(O)=O

InChI Key InChIKey=SDHWYNKMRJOEAU-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 392662   

TargetMelanocortin receptor 4(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392662(US10301286, Example 88)
Affinity DataEC50:  12nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
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TargetMelanocyte-stimulating hormone receptor(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392662(US10301286, Example 88)
Affinity DataEC50:  2.70E+3nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetMelanocortin receptor 3(Human)
Astellas Pharma

US Patent
LigandPNGBDBM392662(US10301286, Example 88)
Affinity DataEC50:  880nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM392662(US10301286, Example 88)
Affinity DataEC50:  11nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent