BDBM392432 N-[2-(4-cyano-3-morpholino-phenyl)- 1H-pyrrolo[2,3-b]pyridin-5-yl]-3,4- dimethyl-1H-pyrazole-5-carboxamide::US10301280, Compound P-2081

SMILES Cc1n[nH]c(C(=O)Nc2cnc3[nH]c(cc3c2)-c2ccc(C#N)c(c2)N2CCOCC2)c1C

InChI Key InChIKey=FFNAXJGXMSKSJY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392432   

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM392432(N-[2-(4-cyano-3-morpholino-phenyl)- 1H-pyrrolo[2,3...)
Affinity DataKi:  5.50E+3nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

LigandPNGBDBM392432(N-[2-(4-cyano-3-morpholino-phenyl)- 1H-pyrrolo[2,3...)
Affinity DataKi:  1.05E+5nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent