BDBM392384 3,4-dimethyl-N-(1H-pyrrolo[2,3- b]pyridin-5-yl)-1H-pyrazole-5- carboxamide::US10301280, Compound P-2032

SMILES Cc1n[nH]c(C(=O)Nc2cnc3[nH]ccc3c2)c1C

InChI Key InChIKey=BJMQAOASNAIEEC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392384   

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM392384(3,4-dimethyl-N-(1H-pyrrolo[2,3- b]pyridin-5-yl)-1H...)
Affinity DataKi: <1.00E+3nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

LigandPNGBDBM392384(3,4-dimethyl-N-(1H-pyrrolo[2,3- b]pyridin-5-yl)-1H...)
Affinity DataKi:  5.50E+3nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent