BDBM392361 US10301278, Example 54

SMILES Nc1nc(cnc1Sc1cccnc1C(F)(F)F)N1CCC(N)(CO)CC1

InChI Key InChIKey=BIWREMBFOLXXBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392361   

LigandPNGBDBM392361(US10301278, Example 54)
Affinity DataIC50: 170nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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