BDBM392349 US10301278, Example 31b

SMILES C[C@@]1(CN)CCN(C[C@H]1O)c1cnc(Sc2cccnc2C(F)(F)F)c(N)n1

InChI Key InChIKey=CPQFKKZFAQQUET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392349   

LigandPNGBDBM392349(US10301278, Example 31b)
Affinity DataIC50: 64nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent