BDBM392344 US10301278, Example 26

SMILES CC1(N)CCN(CC1)c1cnc(Sc2ccc(F)cc2C(F)(F)F)c(N)n1

InChI Key InChIKey=UUTHQJBDDIJPCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392344   

LigandPNGBDBM392344(US10301278, Example 26)
Affinity DataIC50: 67nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
Entry Details
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