BDBM392343 US10301278, Example 25

SMILES C[C@@]1(N)CCN(C[C@@H]1O)c1cnc(Sc2cccc(Cl)c2Cl)c(N)n1

InChI Key InChIKey=KRZIDTJYVFKXKO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392343   

LigandPNGBDBM392343(US10301278, Example 25)
Affinity DataIC50: 77nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
Entry Details
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