BDBM392310 3-(4-amino-4-methylpiperidin-1-yl)-6-((2,3-dichlorophenyl)thio)-1,2,4-triazin-5-amine::US10301278, Example 14

SMILES CC1(N)CCN(CC1)c1nnc(Sc2cccc(Cl)c2Cl)c(N)n1

InChI Key InChIKey=YDTMBAVARCZVKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392310   

LigandPNGBDBM392310(3-(4-amino-4-methylpiperidin-1-yl)-6-((2,3-dichlor...)
Affinity DataIC50: 143nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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