BDBM391896 N-((1-methyl-1H-pyrazol-4- yl)methyl)-2',3'- dihydrospiro[cyclopropane- 1,1'-inden]-2-amine::US10301253, Example 47

SMILES Cn1cc(CNC2CC22CCc3ccccc23)cn1

InChI Key InChIKey=XITORHDZEVGCNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391896   

TargetLysine-specific histone demethylase 1A(Human)
Genentech

US Patent
LigandPNGBDBM391896(US10301253, Example 47 | N-((1-methyl-1H-pyrazol-4...)
Affinity DataIC50: 55.5nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Genentech

US Patent
LigandPNGBDBM391896(US10301253, Example 47 | N-((1-methyl-1H-pyrazol-4...)
Affinity DataIC50: 81.3nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent