BDBM391627 US10300048, ETI-T-174

SMILES COc1ccc(\C=C2/S\C(=N/c3ccc(OC)cc3)N(C2=O)c2ccc(OC)cc2)cc1

InChI Key InChIKey=MEVSHNUCCHKUCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391627   

TargetFatty-acid amide hydrolase 1(Human)
Universitat Bern

US Patent
LigandPNGBDBM391627(US10300048, ETI-T-174)
Affinity DataIC50: 148nMAssay Description:Screening for AEA cellular uptake inhibition was performed in a semi-automated procedure: Pipetting and washing steps were performed by a Biomek3000 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetFatty-acid amide hydrolase 1(Human)
Universitat Bern

US Patent
LigandPNGBDBM391627(US10300048, ETI-T-174)
Affinity DataIC50: 2.04E+4nMAssay Description:Hydrolysis of [3H]-AEA by FAAH was determined as previously described in cell homogenates of U937 cells (0.18 mg protein) (Omeir et al., 1999, Bioche...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent