BDBM390716 (S)-1-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-3-(4-cyclopropylphenyl)urea::US9957261, Example 72

SMILES N[C@H]1CCc2cc(NC(=O)Nc3ccc(cc3)C3CC3)ccc2C1

InChI Key InChIKey=OBNMVTNIQHFERD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390716   

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM390716(US9957261, Example 72 | (S)-1-(6-Amino-5,6,7,8-tet...)
Affinity DataKi:  0.900nMAssay Description:Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM390716(US9957261, Example 72 | (S)-1-(6-Amino-5,6,7,8-tet...)
Affinity DataKi:  1nMAssay Description:Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
Go to US Patent