BDBM390711 (S)-N6-(4-Ethylphenyl)-1,2,3,4-tetrahydronaphthalene-2,6-diamine::US9957261, Example 53

SMILES CCc1ccc(Nc2ccc3C[C@@H](N)CCc3c2)cc1

InChI Key InChIKey=FSMRGZYFTHHFTF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390711   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM390711(US9957261, Example 53 | (S)-N6-(4-Ethylphenyl)-1,2...)
Affinity DataKi:  6nMAssay Description:Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM390711(US9957261, Example 53 | (S)-N6-(4-Ethylphenyl)-1,2...)
Affinity DataKi:  8.30nMAssay Description:Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
Go to US Patent