BDBM389605 2-{(E)-2-[4- (methylsulfonyl)phenyl]vinyl}-N- propylquinazolin-4-amine::US9951029, 122

SMILES CCCNc1nc(\C=C\c2ccc(cc2)S(C)(=O)=O)nc2ccccc12

InChI Key InChIKey=KSTZBUQVGRBPET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 389605   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vichem Chemie Kutató

US Patent
LigandPNGBDBM389605(US9951029, 122 | 2-{(E)-2-[4- (methylsulfonyl)phen...)
Affinity DataIC50: 3.82E+3nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using Transcreener ADP Assay FP method (BellBrook Labs, Madison,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vichem Chemie Kutató

US Patent
LigandPNGBDBM389605(US9951029, 122 | 2-{(E)-2-[4- (methylsulfonyl)phen...)
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed