BDBM389578 N,N-diethyl-N'-(2-{(E)-2-[4- (methylthio)phenyl]vinyl}quinazolin- 4-yl)ethane-1,2-diamine::US9951029, 77

SMILES CCN(CC)CCNc1nc(\C=C\c2ccc(SC)cc2)nc2ccccc12

InChI Key InChIKey=XITKSHDIMBUDOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 389578   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vichem Chemie Kutató

US Patent
LigandPNGBDBM389578(US9951029, 77 | N,N-diethyl-N'-(2-{(E)-2-[4- (meth...)
Affinity DataIC50: 1.76E+3nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using Transcreener ADP Assay FP method (BellBrook Labs, Madison,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vichem Chemie Kutató

US Patent
LigandPNGBDBM389578(US9951029, 77 | N,N-diethyl-N'-(2-{(E)-2-[4- (meth...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed