BDBM388464 US10329256, Example 4::US9944601, Example 4

SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1

InChI Key InChIKey=SMTKWAMFWDROPC-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 388464   

TargetAmine oxidase [flavin-containing] A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataIC50: 3.99E+4nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataIC50: 3.18E+3nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataIC50: 19nMAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataIC50: 3.99E+4nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataIC50: 3.18E+3nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataIC50: 19nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataKi:  55nMAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataKi:  55nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataKi:  5.50E+3nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataKi:  5.50E+3nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataKi:  5.50E+4nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Oryzon Genomics

US Patent
LigandPNGBDBM388464(US10329256, Example 4 | US9944601, Example 4)
Affinity DataKi:  5.50E+4nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent