BDBM388457 4-{4-[(trans-4- morpholin-4- ylcyclohexyl)amino] quinazolin-6-yl} cyclohexanecarboxylic acid::US9943516, 3-6

SMILES OC(=O)C1CCC(CC1)c1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c2c1

InChI Key InChIKey=XYXVIHAKEGCCLG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 388457   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM388457(US9943516, 3-6 | 4-{4-[(trans-4- morpholin-4- ylcy...)
Affinity DataIC50: 98nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
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