BDBM388443 N'-(6- cyclopropylquinazolin- 4-yl)-N,N- dimethylcyclohexane- 1,4-diamine::US9943516, 1-2

SMILES CN(C)C1CCC(CC1)Nc1ncnc2ccc(cc12)C1CC1

InChI Key InChIKey=KDYOOMNKHFSPSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 388443   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM388443(US9943516, 1-2 | N'-(6- cyclopropylquinazolin- 4-y...)
Affinity DataIC50: 12nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
Go to US Patent