BDBM387356 N3-(3-Chloro- 4-fluorophenyl) furo[2,3- c]pyridine-2,3- diamine::US10294212, No. 2

SMILES Nc1oc2cnccc2c1Nc1ccc(F)c(Cl)c1

InChI Key InChIKey=MAFDXEXXQIAQTR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 387356   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Curadev Pharma

US Patent
LigandPNGBDBM387356(US10294212, No. 2 | N3-(3-Chloro- 4-fluorophenyl) ...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 2(Human)
Curadev Pharma

US Patent
LigandPNGBDBM387356(US10294212, No. 2 | N3-(3-Chloro- 4-fluorophenyl) ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human indoleamine 2,3-dioxygenase-2 (hIDO2) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Curadev Pharma

US Patent
LigandPNGBDBM387356(US10294212, No. 2 | N3-(3-Chloro- 4-fluorophenyl) ...)
Affinity DataIC50: 200nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed