BDBM387332 N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]-6-(trifluoromethyl)quinolin-4-amine::US10292985, Example 16

SMILES Cc1cccc(n1)-c1nc(Nc2ccnc3ccc(cc23)C(F)(F)F)c2cccn2n1

InChI Key InChIKey=AARLQNGNXYMABQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387332   

TargetTGF-beta receptor type-1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM387332(US10292985, Example 16 | N-[2-(6-methylpyridin-2-y...)
Affinity DataIC50: 940nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
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TargetTGF-beta receptor type-2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM387332(US10292985, Example 16 | N-[2-(6-methylpyridin-2-y...)
Affinity DataIC50: 1.50E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
Go to US Patent