BDBM387324 2-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrolo[2,1-f][1,2,4]triazin-2-yl)pyridine::US10292985, Example 8

SMILES c1cc2c(nc(nn2c1)-c1ccccn1)-n1ccc2cnccc12

InChI Key InChIKey=TZLMLVYIGMUVRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387324   

TargetTGF-beta receptor type-1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM387324(US10292985, Example 8 | 2-(4-{1H-pyrrolo[3,2-c]pyr...)
Affinity DataIC50: 1.10nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
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TargetTGF-beta receptor type-2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM387324(US10292985, Example 8 | 2-(4-{1H-pyrrolo[3,2-c]pyr...)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
Go to US Patent