BDBM387307 US10292981, Example 138

SMILES Cc1c(cccc1-c1cnc(NC(=O)C2CCc3ccccc3C2)cn1)-c1nn(C)c(=O)o1

InChI Key InChIKey=UHSLDXRDGJQJQF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387307   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387307(US10292981, Example 138)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent