BDBM387301 N-(2′- (allyloxy)-5′-(5,5- dimethyl-4-oxo-4,5- dihydroisoxazol-3-yl)- [1,1′-biphenyl]-4-yl)- 2,6-difluorobenzamide ::US10292981, Example 132

SMILES CC1(C)ON=C(C1=O)c1ccc(OCC=C)c(c1)-c1ccc(NC(=O)c2c(F)cccc2F)cc1

InChI Key InChIKey=CWKALAKQGXNNIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387301   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387301(US10292981, Example 132 | N-(2′- (allyloxy)-...)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent