BDBM387296 N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol- 3-yl)-2- methylphenyl)pyrazin- 2-yl)-3- fluoroisonicotinamide::US10292981, Example 107

SMILES Cc1ccc(cc1-c1cnc(NC(=O)c2ccncc2F)cn1)C1=NOC(C)(C)C1=O

InChI Key InChIKey=OFWLFXZYHKJIML-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387296   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387296(US10292981, Example 107 | N-(5-(5- (5,5-dimethyl-4...)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent