BDBM387291 2,6- Difluoro-N-(2′- methyl-5′-(4-oxo-1- oxa-2- azaspiro[4.5]dec-2- en-3-yl)-[1,1′- biphenyl]-4- yl)benzamide::US10292981, Example 58

SMILES Cc1ccc(cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1)C1=NOC2(CCCCC2)C1=O

InChI Key InChIKey=CYDWCBHDCLFFMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387291   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387291(US10292981, Example 58 | 2,6- Difluoro-N-(2′...)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent