BDBM387286 2,6- difluoro-N-(5-(5-(4- methoxy-5,5- dimethyl-4,5- dihydroisoxazol-3- yl)-2- methylphenyl)pyrazin- 2-yl)benzamide::US10292981, Example 23

SMILES COC1C(=NOC1(C)C)c1ccc(C)c(c1)-c1cnc(NC(=O)c2c(F)cccc2F)cn1

InChI Key InChIKey=RWYVQTQCSDNUNW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387286   

TargetInterleukin-2(Human)
Lupin

US Patent
LigandPNGBDBM387286(US10292981, Example 23 | 2,6- difluoro-N-(5-(5-(4-...)
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent